Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for DtxR transcription factor family

General statistics
TF regulogs 21
TF regulons 136
TF binding sites 472

DtxR family of transcription factors (also known as DtxR/MntR) includes metal ion-dependent regulators that maintain the iron and manganese homeostasis both in Bacteria and Archaea [22297991]. The DtxR-family regulators usually act as transcriptional repressors, while in some cases they can also function as transcriptional activators [16585752]. Ferrous iron and/or manganese serve as co-repressors for metalloregulators [11282473]. DtxR-family regulators contain an N-terminal HTH DNA binding domain (PF01325) and a C-terminal domain (PF02742) that is responsible for metal ion binding and dimerization.

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Actinobacteria DtxR - Corynebacteriaceae 8 (8) 139
Firmicutes DtxR - Clostridia-3 4 (14) 6
Chloroflexi FetR - Chloroflexia 4 (5) 13
Firmicutes IdeR - Clostridia-3 14 (14) 78
Actinobacteria MntR - Corynebacteriaceae 8 (8) 16
Actinobacteria MntR - Micrococcineae 10 (14) 15
Actinobacteria MntR - Mycobacteriaceae 8 (9) 13
Actinobacteria MntR - Nocardiaceae 4 (4) 10
Chloroflexi MntR - Chloroflexia 5 (5) 9
Firmicutes MntR - Bacillales 11 (11) 16
Firmicutes MntR - Clostridia-1 3 (8) 5
Firmicutes MntR - Enterococcaceae 2 (2) 6
Firmicutes MntR - Lactobacillaceae 8 (15) 14
Firmicutes MntR - Listeriaceae 4 (4) 8
Firmicutes MntR - Staphylococcaceae 7 (7) 15
Firmicutes MntR - Streptococcaceae 14 (15) 37
Proteobacteria/alpha MntR - Rhizobiales 4 (15) 12
Proteobacteria/alpha MntR - Rhodobacterales 3 (15) 5
Proteobacteria/alpha MntR - Rhodospirillales 4 (9) 12
Proteobacteria/gamma MntR - Enterobacteriales 7 (12) 35
Proteobacteria/gamma MntR - Xanthomonadales 4 (4) 8