Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for CtsR transcription factor family

General statistics
TF regulogs 4
TF regulons 43
TF binding sites 198

CtsR family of transcription factors includes highly conserved master regulators of heat-shock response genes in Gram-positive bacteria [20852588]. Under non-stress conditions, CtsR binds its target sites upstream of class III stress response genes (Clp ATPases, ClpP protease) [22247503]. Elevated temperature leads to posttranslational degradation of CtsR protein, releasing CtsR from target promoters and activating transcription of the corresponding genes/operons [22247503]. CtsR-like proteins constitute a unique family (PF05848) that includes a winged HTH DNA binding domain [20852588].

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Firmicutes CtsR - Bacillales 11 (11) 41
Firmicutes CtsR - Lactobacillaceae 10 (15) 44
Firmicutes CtsR - Staphylococcaceae 7 (7) 45
Firmicutes CtsR - Streptococcaceae 15 (15) 68