Collection of regulogs for CtsR transcription factor family
|TF binding sites
CtsR family of transcription factors includes highly conserved master regulators of heat-shock response genes in Gram-positive bacteria . Under non-stress conditions, CtsR binds its target sites upstream of class III stress response genes (Clp ATPases, ClpP protease) . Elevated temperature leads to posttranslational degradation of CtsR protein, releasing CtsR from target promoters and activating transcription of the corresponding genes/operons . CtsR-like proteins constitute a unique family (PF05848) that includes a winged HTH DNA binding domain .