Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for CRP transcription factor family

General statistics
TF regulogs 47
TF regulons 310
TF binding sites 8099

Crp family of transcriptional regulators includes numerous characterized activators/repressors of diverse biological processes. The Crp subfamily of regulators in bacteria senses the cellular concentration of cyclic AMP (cAMP), a second messenger important in many biological processes. In E.coli and other enterobacteria, the cAMP-Crp complex acts as a catabolite activator protein that activates the expression of genes involved in the utilization of alternative carbon sources in response to glucose starvation [16547048]. In several other groups of bacteria (Shewanella, Xanthomonas, Pseudomonas), Crp is not required for catabolite repression but controls anaerobic respiration, amino acid metabolism, virulence and pathogenicity [22081386, 21345179, 12775705]. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Firmicutes ArcR - Staphylococcaceae 5 (7) 6
Proteobacteria/delta CooA - Desulfovibrionales 8 (10) 8
Actinobacteria Crp - Bifidobacteriaceae 10 (10) 52
Bacteroidetes Crp - Bacteroidaceae 11 (11) 113
Cyanobacteria Crp - Cyanobacteria 13 (14) 106
Proteobacteria Crp - Shewanellaceae 16 (16) 2713
Proteobacteria/gamma Crp - Enterobacteriales 12 (12) 2301
Proteobacteria/delta DVU0379 - Desulfovibrionales 3 (10) 3
Proteobacteria/delta DVU3111 - Desulfovibrionales 1 (10) 3
Proteobacteria/delta Dde_1200 - Desulfovibrionales 2 (10) 2
Proteobacteria/delta Ddes_0528, DESPIG_03026 - Desulfovibrionales 2 (10) 4
Proteobacteria/delta Ddes_1411/Ddes_2092 - Desulfovibrionales 1 (10) 8
Proteobacteria/delta Ddes_1827 - Desulfovibrionales 1 (10) 1
Proteobacteria/gamma DeoR - Shewanellaceae 9 (16) 9
Proteobacteria/delta Desal_0494 - Desulfovibrionales 1 (10) 2
Proteobacteria/delta Desal_2066 - Desulfovibrionales 3 (10) 6
Proteobacteria/beta Dnr - Ralstonia 6 (6) 9
Proteobacteria/gamma Dnr - Shewanellaceae 3 (16) 5
Proteobacteria/delta DvMF_1708 - Desulfovibrionales 3 (10) 3
Proteobacteria/alpha FixK - Caulobacterales 4 (4) 25
Firmicutes FlpA - Lactobacillaceae 13 (15) 32
Firmicutes FlpA - Streptococcaceae 2 (15) 4
Firmicutes Fnr - Bacillales 11 (11) 39
Gammaproteobacteria Fnr - Enterobacteriales 12 (12) 685
Proteobacteria/gamma Fnr - Shewanellaceae 16 (16) 541
Proteobacteria/alpha FnrN - Rhodobacterales 12 (15) 85
Proteobacteria/alpha FnrN - Rhodospirillales 8 (9) 18
Proteobacteria/alpha FnrN - Sphingomonadales 5 (7) 23
Proteobacteria/Alpha FnrN/FixK/AadR - Rhizobiales 14 (15) 192
Actinobacteria GlxR - Corynebacteriaceae 8 (8) 562
Bacteroidetes HcpR - Bacteroidaceae 9 (11) 18
Chloroflexi HcpR - Chloroflexia 3 (5) 4
Firmicutes HcpR - Clostridia-1 8 (8) 32
Firmicutes HcpR - Clostridia-2 1 (3) 2
Firmicutes HcpR - Thermoanaerobacterales 2 (7) 4
Proteobacteria/delta HcpR - Desulfovibrionales 7 (10) 25
Proteobacteria/delta HcpR - Desulfuromonadales 9 (9) 44
Thermotogae HcpR - Thermotogales 11 (11) 20
Firmicutes NihR - Lactobacillaceae 5 (15) 10
Proteobacteria NnrR - Caulobacterales 2 (4) 11
Proteobacteria NnrR - Rhizobiales 9 (15) 110
Proteobacteria NnrR - Rhodobacterales 3 (15) 14
Proteobacteria NnrR - Rhodospirillales 1 (9) 5
Proteobacteria NnrR - Sphingomonadales 1 (7) 2
Bacteroidetes NrfR - Bacteroidaceae 6 (11) 6
Cyanobacteria NtcA - Cyanobacteria 14 (14) 228
Proteobacteria/gamma PnuR - Shewanellaceae 4 (16) 4