Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for SiaR transcription factor

General statistics
Genomes 37
TF regulogs 4
TF regulons 15
TF binding sites 63

Transcription factor SiaR from the RpiR protein family regulates the sialic acid utilization genes in Gammaproteobacteria. The SiaR regulon and its DNA-binding motif were discovered by application of the comparative genomic approach and was then experimentally validated in Haemophilus influenzae [20843349]. SiaR is a non-orthologous replacement for the GntR-family NanR regulator of silaic acid utilization in E.coli. Physiological and biochemical studies indicated that glucosamine-6-phosphate, is an inducer which interacts with SiaR, provoking its dissociation from DNA.

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/gamma SiaR - Enterobacteriales 4 (12) 14
Proteobacteria/gamma SiaR - Pasteurellales 7 (9) 23
Proteobacteria/gamma SiaR - Psychromonadaceae/Aeromonadales 1 (6) 9
Proteobacteria/gamma SiaR - Vibrionales 3 (10) 17