Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for NtrC transcription factor

General statistics
Genomes 177
TF regulogs 19
TF regulons 169
TF binding sites 921

Transcription factor NtrC is a member of the two-component NtrB-NtrC system that controls nitrogen assimilation in Proteobacteria. The NtrC regulator was experimentally analyzed in E. coli and some Alphaproteobacteria. NtrC usually acts as a transcriptional repressor but sometimes can act also as an activator of transcription. The NtrC protein contains a C-terminal HTH domain of the Fis family. NtrB functions as a membrane-associated protein kinase that in response to limitation of nitrogen and carbon-limited growth is autophosphorylated. After that, NtrB transfers its phosphate group to NtrC to activate this transcriptional regulator

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/alpha NtrC - Caulobacterales 4 (4) 15
Proteobacteria/alpha NtrC - Desulfuromonadales 9 (9) 56
Proteobacteria/alpha NtrC - Rhizobiales 14 (15) 86
Proteobacteria/alpha NtrC - Rhodobacterales 14 (15) 92
Proteobacteria/alpha NtrC - Rhodospirillales 8 (9) 40
Proteobacteria/alpha NtrC - Sphingomonadales 6 (7) 25
Proteobacteria/beta NtrC - Burkholderia 8 (8) 27
Proteobacteria/beta NtrC - Comamonadaceae 11 (11) 52
Proteobacteria/beta NtrC - Ralstonia 6 (6) 28
Proteobacteria/beta NtrC - Various betaproteobacteria 9 (12) 47
Proteobacteria/gamma NtrC - Alteromonadales 9 (9) 26
Proteobacteria/gamma NtrC - Enterobacteriales 12 (12) 130
Proteobacteria/gamma NtrC - Moraxellaceae 4 (4) 27
Proteobacteria/gamma NtrC - Oceanospirillales/Alteromonadales 12 (12) 63
Proteobacteria/gamma NtrC - Pseudomonadaceae 8 (8) 49
Proteobacteria/gamma NtrC - Psychromonadaceae/Aeromonadales 6 (6) 25
Proteobacteria/gamma NtrC - Shewanellaceae 16 (16) 94
Proteobacteria/gamma NtrC - Vibrionales 9 (10) 29
Proteobacteria/gamma NtrC - Xanthomonadales 4 (4) 10