Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for ModE transcription factor

General statistics
Genomes 216
TF regulogs 31
TF regulons 137
TF binding sites 309

ModE is a dual regulator that controls transcription of genes involved in the homeostasis of molybdenum. ModE-dependent regulation was experimentally characterized in Escherichia coli. ModE regulon includes molybdenum transporters, genes involved in the synthesis of molybdenum cofactors (e.g., molybdopterin guanine dinucleotide in E. coli), and some molybdenum-containing enzymes. The regulatory effect of ModE is induced when E. coli is grown under anaerobic growth conditions and when the physiological inducer, molybdenum, binds to ModE and promotes the dimerization of the ModE-Mo complex. We used a comparative genomics approach to reconstruct transcriptional regulons controlled by ModE orthologs in different lineages of Proteobacteria.

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Bacteroidetes ModE2 - Flavobacteria 2 (19) 2
Chlorobi ModE - Chlorobiales 10 (11) 25
Proteobacteria/Alpha ModE - Rhizobiales 1 (15) 2
Proteobacteria/Apha ModE - Rhodobacterales 1 (15) 3
Proteobacteria/Beta ModE3 - Alcaligenaceae 2 (3) 5
Proteobacteria/Beta ModE2 - Burkholderia 4 (8) 10
Proteobacteria/Beta ModE2 - Comamonadaceae 5 (11) 8
Proteobacteria/Beta ModE3 - Comamonadaceae 7 (11) 12
Proteobacteria/Beta ModE3 - Ralstonia 6 (6) 12
Proteobacteria/Beta ModE2 - Various betaproteobacteria 2 (12) 4
Proteobacteria/alpha ModE - Caulobacterales 2 (4) 5
Proteobacteria/alpha ModE - Rhizobiales 9 (15) 12
Proteobacteria/alpha ModE2 - Rhodobacterales 4 (15) 5
Proteobacteria/alpha ModE - Rhodospirillales 2 (9) 7
Proteobacteria/alpha ModE2 - Rhodospirillales 2 (9) 2
Proteobacteria/alpha ModE2 - Sphingomonadales 2 (7) 2
Proteobacteria/beta ModE - Alcaligenaceae 3 (3) 3
Proteobacteria/beta ModE - Burkholderia 7 (8) 8
Proteobacteria/beta ModE - Comamonadaceae 6 (11) 10
Proteobacteria/beta ModE - Ralstonia 6 (6) 8
Proteobacteria/beta ModE - Various betaproteobacteria 2 (12) 3
Proteobacteria/delta ModE2 - Desulfovibrionales 7 (10) 48
Proteobacteria/delta ModE - Desulfuromonadales 7 (9) 10
Proteobacteria/gamma ModE - Enterobacteriales 12 (12) 55
Proteobacteria/gamma ModE - Moraxellaceae 1 (4) 1
Proteobacteria/gamma ModE - Oceanospirillales/Alteromonadales 2 (12) 2
Proteobacteria/gamma ModE - Pasteurellales 6 (9) 21
Proteobacteria/gamma ModE - Pseudomonadaceae 8 (8) 9
Proteobacteria/gamma ModE - Psychromonadaceae/Aeromonadales 2 (6) 3
Proteobacteria/gamma ModE - Shewanellaceae 5 (16) 10
Proteobacteria/gamma ModE - Vibrionales 2 (10) 2