Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for LexA transcription factor

General statistics
Genomes 339
TF regulogs 39
TF regulons 315
TF binding sites 3025

LexA protein belongs to the LexA family and acts mostly as a repressor; in some cases LexA can also activate transcription. LexA regulation was experimentally analyzed in different species from the Proteobacteria, Cyanobacteria, Firmicutes, Actinobacteria, and Chloroflexi phyla. Under the condition of DNA damage, the LexA repressor dissociates from its DNA target sites and the LexA regulon is induced. The dissociation is caused by self-cleavage of LexA protein as a result interaction with the RecA-ssDNA-ATP complex. The SOS response regulon LexA includes a large set of genes involved in DNA reparation. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Actinobacteria LexA - Bifidobacteriaceae 10 (10) 97
Actinobacteria LexA - Corynebacteriaceae 8 (8) 109
Actinobacteria LexA - Frankineae/Propionibacterineae/Pseudonocardiaceae 9 (9) 68
Actinobacteria LexA - Micrococcineae 12 (14) 62
Actinobacteria LexA - Mycobacteriaceae 9 (9) 83
Actinobacteria LexA - Nocardiaceae 4 (4) 33
Actinobacteria LexA - Streptomycetaceae 4 (4) 26
Chloroflexi LexA - Chloroflexia 5 (5) 52
Cyanobacteria LexA - Cyanobacteria 10 (14) 26
Firmicutes LexA - Bacillales 11 (11) 206
Firmicutes LexA - Clostridia-1 8 (8) 27
Firmicutes LexA - Clostridia-2 3 (3) 11
Firmicutes LexA - Clostridia-3 14 (14) 102
Firmicutes LexA - Lactobacillaceae 15 (15) 99
Firmicutes LexA - Listeriaceae 4 (4) 48
Firmicutes LexA - Staphylococcaceae 7 (7) 85
Planctomycetes LexA - Planctomycetes 5 (5) 9
Proteobacteria LexA - Desulfuromonadales 6 (9) 11
Proteobacteria LexA - Rhodobacterales 15 (15) 128
Proteobacteria/alpha LexA - Caulobacterales 4 (4) 47
Proteobacteria/alpha LexA - Rhizobiales 15 (15) 212
Proteobacteria/alpha LexA - Rhodospirillales 9 (9) 52
Proteobacteria/alpha LexA - Sphingomonadales 7 (7) 61
Proteobacteria/beta LexA - Alcaligenaceae 3 (3) 19
Proteobacteria/beta LexA - Burkholderia 8 (8) 75
Proteobacteria/beta LexA - Comamonadaceae 11 (11) 71
Proteobacteria/beta LexA - Ralstonia 6 (6) 62
Proteobacteria/beta LexA - Various betaproteobacteria 4 (12) 12
Proteobacteria/delta LexA - Desulfovibrionales 1 (10) 4
Proteobacteria/gamma LexA - Alteromonadales 9 (9) 111
Proteobacteria/gamma LexA - Enterobacteriales 12 (12) 265
Proteobacteria/gamma LexA - Oceanospirillales/Alteromonadales 12 (12) 91
Proteobacteria/gamma LexA - Pasteurellales 9 (9) 96
Proteobacteria/gamma LexA - Pseudomonadaceae 8 (8) 101
Proteobacteria/gamma LexA - Psychromonadaceae/Aeromonadales 6 (6) 77
Proteobacteria/gamma LexA - Shewanellaceae 16 (16) 192
Proteobacteria/gamma LexA - Vibrionales 10 (10) 186
Proteobacteria/gamma LexA - Xanthomonadales 4 (4) 7
Proteobacteria/gamma LexA2 - Xanthomonadales 2 (4) 2