Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for NagC transcription factor

General statistics
Genomes 49
TF regulogs 5
TF regulons 31
TF binding sites 304

Transcription factor NagC from the ROK protein family regulates the chitin and N-acetylglucosamine utilization genes in Gammaproteobacteria. It was originally characterized in E. coli as a repressor of the nag catabolic genes, and later it was shown to act as an activator of the biosynthetic glmSU genes. Physiological and biochemical studies indicated that N-acetylglucosamine-6P, is an inducer which interacts with NagC, provoking its dissociation from DNA. The comparative genomic approach was used to reconstruct orthologous NagC regulons in the Enterobacteriales, and other lineages of Gammaproteobacteria [16857666].

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/gamma NagC - Enterobacteriales 12 (12) 68
Proteobacteria/gamma NagC - Oceanospirillales/Alteromonadales 1 (12) 5
Proteobacteria/gamma NagC - Pasteurellales 2 (9) 16
Proteobacteria/gamma NagC - Psychromonadaceae/Aeromonadales 6 (6) 16
Proteobacteria/gamma NagC - Vibrionales 10 (10) 199