Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for SoxR transcription factor

General statistics
Genomes 164
TF regulogs 17
TF regulons 71
TF binding sites 157

Transcription factor SoxR from the MerR protein family regulates superoxide response regulons in Proteobacteria. It was first identified in E. coli as a [2Fe-2S]-containing sensor-regulator, which is activated through oxidation by redox-active compounds [25490746]. The SoxR repressor in E.coli and other Enterobacteria is a part of regulatory cascade with the SoxS transcriptional activator of superoxide response regulon [8306957]. However, in other Proteobacteria including Pseudomonas and Streptomyces spp., SoxR regulons lack the genes required for stress responses. In Pseudomonas aeruginosa, SoxR regulates the efflux of phenazines via the RND transporter MexGHI-OpmD [18755976].

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/Alpha SoxR - Rhizobiales 7 (15) 22
Proteobacteria/Alpha SoxR - Rhodobacterales 8 (15) 18
Proteobacteria/Beta SoxR - Burkholderia 3 (8) 8
Proteobacteria/Beta SoxR - Comamonadaceae 5 (11) 12
Proteobacteria/Gamma SoxR - Enterobacteriales 6 (12) 14
Proteobacteria/Gamma SoxR - Pseudomonadaceae 5 (8) 16
Proteobacteria/Gamma SoxR - Vibrionales 8 (10) 24
Proteobacteria/Gamma SoxR - Xanthomonadales 3 (4) 10
Proteobacteria/alpha SoxR - Rhodospirillales 1 (9) 1
Proteobacteria/alpha SoxR - Sphingomonadales 4 (7) 5
Proteobacteria/beta SoxR - Ralstonia 3 (6) 3
Proteobacteria/beta SoxR - Various betaproteobacteria 1 (12) 1
Proteobacteria/gamma SoxR - Alteromonadales 3 (9) 3
Proteobacteria/gamma SoxR - Moraxellaceae 2 (4) 2
Proteobacteria/gamma SoxR - Oceanospirillales/Alteromonadales 3 (12) 3
Proteobacteria/gamma SoxR - Psychromonadaceae/Aeromonadales 3 (6) 3
Proteobacteria/gamma SoxR - Shewanellaceae 6 (16) 12