Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for PhrR transcription factor

General statistics
Genomes 40
TF regulogs 4
TF regulons 23
TF binding sites 84

Transcription factor PhrR from the MerR protein family binds vitamin B12 as a cofactor and regulates genes in response to blue light. PhrR regulators identified in Proteobacteria by comparative genomes are homologous to the light-inducible LitR repressors from Firmicutes and Thermus spp that are composed of an N-terminal DNA-binding domain from the MerR family and a C-terminal B12-binding domain. The identified novel group of LitR-related transcriptional regulators that control phr genes in gamma-proteobacteria was termed PhrR (for a Phr regulator). The comparative analysis of the reconstructed regulons revealed considerable variability in the regulon content between the analyzed lineages of gamma-proteobacteria.

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/Gamma PhrR - Pseudomonadaceae 8 (8) 43
Proteobacteria/Gamma PhrR - Psychromonadaceae/Aeromonadales 2 (6) 4
Proteobacteria/Gamma PhrR - Shewanellaceae 7 (16) 21
Proteobacteria/Gamma PhrR - Vibrionales 6 (10) 16