Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for HcpR transcription factor

General statistics
Genomes 64
TF regulogs 8
TF regulons 50
TF binding sites 149

Transcription factor HcpR from the CRP protein family regulates genes of nitrite stress response. The primary targets of HcpR are the hybrid-cluster protein Hcp, which has a protective role in nitrite stress conditions, and the associated ferredoxin-like proteins. HcpR is present in diverse anaerobic bacteria, including Clostridia, Thermotogales, and delta-proteobacteria [PMID 16261196]. HcpR was initially discovered with comparative genomic approach and then was experimentally studied in Porphyromonas gingivalis and Desulfovibrio species [PMID 22778102, 21265778, 26273559]

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Bacteroidetes HcpR - Bacteroidaceae 9 (11) 18
Chloroflexi HcpR - Chloroflexia 3 (5) 4
Firmicutes HcpR - Clostridia-1 8 (8) 32
Firmicutes HcpR - Clostridia-2 1 (3) 2
Firmicutes HcpR - Thermoanaerobacterales 2 (7) 4
Proteobacteria/delta HcpR - Desulfovibrionales 7 (10) 25
Proteobacteria/delta HcpR - Desulfuromonadales 9 (9) 44
Thermotogae HcpR - Thermotogales 11 (11) 20