Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for TyrR transcription factor

General statistics
Genomes 70
TF regulogs 8
TF regulons 67
TF binding sites 618

Transcription factor TyrR belongs to the Fis protein family and can act both as a repressor and as an activator of transcription at sigma-70-dependent promoters. The TyrR regulon controls genes that are essential for aromatic amino acid biosynthesis, transport, and catabolism. In E. coli, the tyrosine- and phenylalanine-responsive regulator TyrR represses most aromatic amino acid biosynthetic enzymes and transporters encoded by multiple aro and tyr genes scattered on the chromosome, and activates the tyrosine transporter encoded by the mtr gene. Its ortholog in Pseudomonas spp., known as PhhR, is a regulator responsible for activation of genes essential for phenylalanine degradation and homeostasis. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/Gamma TyrR1 - Alteromonadales 7 (9) 32
Proteobacteria/Gamma TyrR2 - Alteromonadales 2 (9) 7
Proteobacteria/Gamma TyrR - Vibrionales 10 (10) 83
Proteobacteria/gamma TyrR - Enterobacteriales 12 (12) 106
Proteobacteria/gamma TyrR - Pasteurellales 9 (9) 29
Proteobacteria/gamma PhhR - Pseudomonadaceae 7 (8) 32
Proteobacteria/gamma TyrR - Psychromonadaceae/Aeromonadales 4 (6) 17
Proteobacteria/gamma TyrR - Shewanellaceae 16 (16) 312