Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for NifA transcription factor

General statistics
Genomes 46
TF regulogs 4
TF regulons 19
TF binding sites 202

Transcription factor NifA from the Fis family is a master regulator of nitrogen fixation in nitrogen-fixing Proteobacteria. The NifA protein activates the nitrogenase-coding genes in association with the RNA-polymerase sigma factor RpoN [7968919, 12003951]. NifA protein recognizes the palingromic DNA motif with the consensus TGT-N10-ACA [10536136]. In some Rhizobiales NifA also controls genes for denitrification, and respiration [16788198,19840105, 17569992]. We used comparative genomics approach to reconstruct transcriptional regulons controlled by NifA regulators in Alphaproteobacteria.

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/alpha NifA - Rhizobiales 11 (15) 130
Proteobacteria/alpha NifA - Rhodobacterales 1 (15) 12
Proteobacteria/alpha NifA - Rhodospirillales 6 (9) 54
Proteobacteria/alpha NifA - Sphingomonadales 1 (7) 6