Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for MetJ transcription factor

General statistics
Genomes 62
TF regulogs 6
TF regulons 62
TF binding sites 1026

Transcription repressor MetJ regulates the methionine metabolism in Gamma-proteobacteria. MetJ belongs to the ribbon-helix-helix family of regulatory proteins. It was originally characterized in E. coli as a repressor of genes involved in biosynthesis and transport of methionine [1943695]. MetJ as a homodimer recognizes and binds to an 8-bp DNA sequence called the met-box [1406951]. The affinity of MetJ to this site is enhanced by S-adenosylmethionine [2677754]. The comparative genomic approach was used to reconstruct orthologous MetJ regulons in Gamma-proteobacteria [22082356].

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/Gamma MetJ - Alteromonadales 9 (9) 110
Proteobacteria/Gamma MetJ - Enterobacteriales 12 (12) 167
Proteobacteria/Gamma MetJ - Pasteurellales 9 (9) 50
Proteobacteria/Gamma MetJ - Psychromonadaceae/Aeromonadales 6 (6) 84
Proteobacteria/Gamma MetJ - Vibrionales 10 (10) 218
Proteobacteria/gamma MetJ - Shewanellaceae 16 (16) 397