Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs in Staphylococcaceae taxonomic group

General statistics
Genomes 7
TF regulogs 52
TF regulons 281
TF binding sites 1970
RNA regulogs 29
RNA regulons 194
RNA sites 288

This collection involves all regulons that were tentatively predicted by applying integrative comparative genomic approach to a single taxonomic group of closely-related genomes. To infer the regulons operated by transcription factors (TFs), we combined the identification of TF binding sites and cross-genome comparison of regulons with the analysis of the genomic and functional context of candidate target genes. To infer the regulons operated by regulatory RNAs such as riboswitches, we identified candidate RNA regulatory elements using HMM profiles and further analyzed their genomic and functional context.

Studied genomes and reconstructed regulon statistics
TF RNA Total
Genomes Regulons Sites Regulons Sites Regulons Sites
Macrococcus caseolyticus JCSC5402 31 146 27 45 58 191
Staphylococcus aureus subsp. aureus N315 49 402 27 36 76 438
Staphylococcus capitis SK14 41 296 27 38 68 334
Staphylococcus carnosus subsp. carnosus TM300 40 267 28 45 68 312
Staphylococcus epidermidis ATCC 12228 38 274 28 40 66 314
Staphylococcus haemolyticus JCSC1435 41 297 28 42 69 339
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 41 288 29 42 70 330
Genomic distribution of regulons
Family Type Regulator Function
ArgR TF ArgR
6 ArgR

Staphylococcus aureus subsp. aureus N315
4 ArgR

Staphylococcus capitis SK14
7 ArgR

Staphylococcus epidermidis ATCC 12228
5 ArgR

Staphylococcus carnosus subsp. carnosus TM300
5 ArgR

Staphylococcus haemolyticus JCSC1435
5 ArgR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
3 ArgR

Macrococcus caseolyticus JCSC5402
Arginine biosynthesis; Arginine degradation
ArsR TF ArsR
2 ArsR

Staphylococcus aureus subsp. aureus N315
1 ArsR

Staphylococcus capitis SK14
2 ArsR

Staphylococcus epidermidis ATCC 12228
3 ArsR

Staphylococcus haemolyticus JCSC1435
3 ArsR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 ArsR

Macrococcus caseolyticus JCSC5402
Arsenic resistance
TF CzrA
1 CzrA

Staphylococcus aureus subsp. aureus N315
1 CzrA

Staphylococcus capitis SK14
1 CzrA

Staphylococcus epidermidis ATCC 12228
1 CzrA

Staphylococcus carnosus subsp. carnosus TM300
1 CzrA

Staphylococcus haemolyticus JCSC1435
1 CzrA

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Zinc resistance
BglG TF ManR
1 ManR

Staphylococcus aureus subsp. aureus N315
1 ManR

Staphylococcus capitis SK14
1 ManR

Staphylococcus epidermidis ATCC 12228
1 ManR

Staphylococcus carnosus subsp. carnosus TM300
Mannose utilization
TF MtlR
1 MtlR

Staphylococcus aureus subsp. aureus N315
1 MtlR

Staphylococcus capitis SK14
1 MtlR

Staphylococcus carnosus subsp. carnosus TM300
1 MtlR

Staphylococcus haemolyticus JCSC1435
1 MtlR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Mannitol utilization
BirA TF BirA
3 BirA

Staphylococcus aureus subsp. aureus N315
3 BirA

Staphylococcus capitis SK14
4 BirA

Staphylococcus epidermidis ATCC 12228
4 BirA

Staphylococcus carnosus subsp. carnosus TM300
3 BirA

Staphylococcus haemolyticus JCSC1435
2 BirA

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 BirA

Macrococcus caseolyticus JCSC5402
Biotin biosynthesis
CRP TF ArcR
1 ArcR

Staphylococcus aureus subsp. aureus N315
1 ArcR

Staphylococcus capitis SK14
2 ArcR

Staphylococcus epidermidis ATCC 12228
1 ArcR

Staphylococcus carnosus subsp. carnosus TM300
1 ArcR

Staphylococcus haemolyticus JCSC1435
Arginine degradation
CodY TF CodY
66 CodY

Staphylococcus aureus subsp. aureus N315
57 CodY

Staphylococcus capitis SK14
53 CodY

Staphylococcus epidermidis ATCC 12228
51 CodY

Staphylococcus carnosus subsp. carnosus TM300
59 CodY

Staphylococcus haemolyticus JCSC1435
50 CodY

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
22 CodY

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
CtsR TF CtsR
6 CtsR

Staphylococcus aureus subsp. aureus N315
6 CtsR

Staphylococcus capitis SK14
6 CtsR

Staphylococcus epidermidis ATCC 12228
6 CtsR

Staphylococcus carnosus subsp. carnosus TM300
6 CtsR

Staphylococcus haemolyticus JCSC1435
5 CtsR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
4 CtsR

Macrococcus caseolyticus JCSC5402
Heat shock response
DeoR TF FruR
1 FruR

Staphylococcus aureus subsp. aureus N315
1 FruR

Staphylococcus capitis SK14
1 FruR

Staphylococcus epidermidis ATCC 12228
1 FruR

Staphylococcus carnosus subsp. carnosus TM300
1 FruR

Staphylococcus haemolyticus JCSC1435
1 FruR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 FruR

Macrococcus caseolyticus JCSC5402
Fructose utilization
TF LacR
1 LacR

Staphylococcus aureus subsp. aureus N315
1 LacR

Staphylococcus capitis SK14
1 LacR

Staphylococcus epidermidis ATCC 12228
1 LacR

Staphylococcus haemolyticus JCSC1435
Lactose utilization
DtxR TF MntR
2 MntR

Staphylococcus aureus subsp. aureus N315
2 MntR

Staphylococcus capitis SK14
2 MntR

Staphylococcus epidermidis ATCC 12228
2 MntR

Staphylococcus carnosus subsp. carnosus TM300
2 MntR

Staphylococcus haemolyticus JCSC1435
2 MntR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 MntR

Macrococcus caseolyticus JCSC5402
Manganese homeostasis
FUR TF Fur
20 Fur

Staphylococcus aureus subsp. aureus N315
15 Fur

Staphylococcus capitis SK14
10 Fur

Staphylococcus epidermidis ATCC 12228
14 Fur

Staphylococcus carnosus subsp. carnosus TM300
14 Fur

Staphylococcus haemolyticus JCSC1435
15 Fur

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
7 Fur

Macrococcus caseolyticus JCSC5402
Iron homeostasis
TF PerR
10 PerR

Staphylococcus aureus subsp. aureus N315
8 PerR

Staphylococcus capitis SK14
6 PerR

Staphylococcus epidermidis ATCC 12228
7 PerR

Staphylococcus carnosus subsp. carnosus TM300
9 PerR

Staphylococcus haemolyticus JCSC1435
7 PerR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
7 PerR

Macrococcus caseolyticus JCSC5402
Oxidative stress response
TF Zur
8 Zur

Staphylococcus aureus subsp. aureus N315
9 Zur

Staphylococcus capitis SK14
7 Zur

Staphylococcus epidermidis ATCC 12228
8 Zur

Staphylococcus carnosus subsp. carnosus TM300
10 Zur

Staphylococcus haemolyticus JCSC1435
7 Zur

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 Zur

Macrococcus caseolyticus JCSC5402
Zinc homeostasis
FapR TF FapR
4 FapR

Staphylococcus aureus subsp. aureus N315
5 FapR

Staphylococcus capitis SK14
4 FapR

Staphylococcus epidermidis ATCC 12228
3 FapR

Staphylococcus carnosus subsp. carnosus TM300
5 FapR

Staphylococcus haemolyticus JCSC1435
4 FapR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
5 FapR

Macrococcus caseolyticus JCSC5402
Fatty acid biosynthesis
GntR/MocR TF GabR
1 GabR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Gamma-aminobutyrate utilization
TF PdxR
1 PdxR

Staphylococcus aureus subsp. aureus N315
1 PdxR

Staphylococcus capitis SK14
1 PdxR

Staphylococcus epidermidis ATCC 12228
1 PdxR

Staphylococcus carnosus subsp. carnosus TM300
1 PdxR

Staphylococcus haemolyticus JCSC1435
1 PdxR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 PdxR

Macrococcus caseolyticus JCSC5402
Pyridoxine biosynthesis
TF YdfD/YisV
1 YdfD/YisV

Staphylococcus aureus subsp. aureus N315
1 YdfD/YisV

Staphylococcus capitis SK14
1 YdfD/YisV

Staphylococcus carnosus subsp. carnosus TM300
1 YdfD/YisV

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Metabolite transport
TF YhdI/YdeL
1 YhdI/YdeL

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Metabolite transport
GntR/Others TF BglR
2 BglR

Staphylococcus aureus subsp. aureus N315
Beta-glucosides utilization
TF GntR
1 GntR

Staphylococcus aureus subsp. aureus N315
1 GntR

Staphylococcus capitis SK14
1 GntR

Staphylococcus epidermidis ATCC 12228
1 GntR

Staphylococcus carnosus subsp. carnosus TM300
1 GntR

Staphylococcus haemolyticus JCSC1435
1 GntR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 GntR

Macrococcus caseolyticus JCSC5402
Gluconate utilization
TF TreR
1 TreR

Staphylococcus aureus subsp. aureus N315
1 TreR

Staphylococcus carnosus subsp. carnosus TM300
1 TreR

Staphylococcus haemolyticus JCSC1435
1 TreR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 TreR

Macrococcus caseolyticus JCSC5402
Trehalose utilization
TF YtrA
1 YtrA

Staphylococcus aureus subsp. aureus N315
1 YtrA

Staphylococcus capitis SK14
1 YtrA

Staphylococcus epidermidis ATCC 12228
1 YtrA

Staphylococcus carnosus subsp. carnosus TM300
1 YtrA

Staphylococcus haemolyticus JCSC1435
1 YtrA

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Hypothetical ABC transporter
TF YtrA2
1 YtrA2

Macrococcus caseolyticus JCSC5402
Multidrug resistance; Multidrug efflux; Antibiotic resistance
HrcA TF HrcA
2 HrcA

Staphylococcus aureus subsp. aureus N315
2 HrcA

Staphylococcus capitis SK14
2 HrcA

Staphylococcus epidermidis ATCC 12228
2 HrcA

Staphylococcus carnosus subsp. carnosus TM300
2 HrcA

Staphylococcus haemolyticus JCSC1435
2 HrcA

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 HrcA

Macrococcus caseolyticus JCSC5402
Heat shock response
LacI TF CcpA
73 CcpA

Staphylococcus aureus subsp. aureus N315
54 CcpA

Staphylococcus capitis SK14
47 CcpA

Staphylococcus epidermidis ATCC 12228
53 CcpA

Staphylococcus carnosus subsp. carnosus TM300
54 CcpA

Staphylococcus haemolyticus JCSC1435
64 CcpA

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
24 CcpA

Macrococcus caseolyticus JCSC5402
Carbon catabolism
TF MalR
2 MalR

Staphylococcus aureus subsp. aureus N315
1 MalR

Staphylococcus haemolyticus JCSC1435
1 MalR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 MalR

Macrococcus caseolyticus JCSC5402
Maltose utilization; Maltodextrin utilization
TF RbsR
1 RbsR

Staphylococcus aureus subsp. aureus N315
1 RbsR

Staphylococcus carnosus subsp. carnosus TM300
Ribose utilization
TF RbsR2
1 RbsR2

Staphylococcus aureus subsp. aureus N315
1 RbsR2

Staphylococcus epidermidis ATCC 12228
1 RbsR2

Staphylococcus carnosus subsp. carnosus TM300
1 RbsR2

Staphylococcus haemolyticus JCSC1435
2 RbsR2

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 RbsR2

Macrococcus caseolyticus JCSC5402
Ribose utilization
TF ScrR
2 ScrR

Staphylococcus aureus subsp. aureus N315
2 ScrR

Staphylococcus capitis SK14
2 ScrR

Staphylococcus epidermidis ATCC 12228
2 ScrR

Staphylococcus haemolyticus JCSC1435
2 ScrR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 ScrR

Macrococcus caseolyticus JCSC5402
Sucrose utilization
LexA TF LexA
10 LexA

Staphylococcus aureus subsp. aureus N315
10 LexA

Staphylococcus capitis SK14
10 LexA

Staphylococcus epidermidis ATCC 12228
8 LexA

Staphylococcus carnosus subsp. carnosus TM300
10 LexA

Staphylococcus haemolyticus JCSC1435
10 LexA

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
6 LexA

Macrococcus caseolyticus JCSC5402
SOS response
LysR TF GltC
2 GltC

Staphylococcus aureus subsp. aureus N315
2 GltC

Staphylococcus capitis SK14
2 GltC

Staphylococcus epidermidis ATCC 12228
2 GltC

Staphylococcus carnosus subsp. carnosus TM300
2 GltC

Staphylococcus haemolyticus JCSC1435
2 GltC

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Glutamate metabolism
TF HutR
3 HutR

Staphylococcus aureus subsp. aureus N315
2 HutR

Staphylococcus capitis SK14
2 HutR

Staphylococcus carnosus subsp. carnosus TM300
2 HutR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 HutR

Macrococcus caseolyticus JCSC5402
Histidine utilization
LytTR TF AgrA
2 AgrA

Staphylococcus aureus subsp. aureus N315
1 AgrA

Staphylococcus capitis SK14
1 AgrA

Staphylococcus epidermidis ATCC 12228
1 AgrA

Staphylococcus carnosus subsp. carnosus TM300
1 AgrA

Staphylococcus haemolyticus JCSC1435
1 AgrA

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Virulence; Quorum sensing
MarR TF BlaI
2 BlaI

Staphylococcus aureus subsp. aureus N315
2 BlaI

Staphylococcus capitis SK14
2 BlaI

Staphylococcus epidermidis ATCC 12228
2 BlaI

Staphylococcus haemolyticus JCSC1435
Beta-lactam resistance
TF MecI
2 MecI

Staphylococcus aureus subsp. aureus N315
Penicillin and methicillin resistance
TF MepR
2 MepR

Staphylococcus aureus subsp. aureus N315
2 MepR

Staphylococcus carnosus subsp. carnosus TM300
2 MepR

Staphylococcus haemolyticus JCSC1435
2 MepR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Multidrug resistance
MerR TF GlnR
2 GlnR

Staphylococcus aureus subsp. aureus N315
2 GlnR

Staphylococcus capitis SK14
2 GlnR

Staphylococcus epidermidis ATCC 12228
1 GlnR

Staphylococcus carnosus subsp. carnosus TM300
2 GlnR

Staphylococcus haemolyticus JCSC1435
2 GlnR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 GlnR

Macrococcus caseolyticus JCSC5402
Nitrogen assimilation
NrdR TF NrdR
2 NrdR

Staphylococcus aureus subsp. aureus N315
2 NrdR

Staphylococcus capitis SK14
2 NrdR

Staphylococcus epidermidis ATCC 12228
2 NrdR

Staphylococcus carnosus subsp. carnosus TM300
1 NrdR

Staphylococcus haemolyticus JCSC1435
2 NrdR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 NrdR

Macrococcus caseolyticus JCSC5402
Deoxyribonucleotide biosynthesis
OmpR TF HssR
1 HssR

Staphylococcus aureus subsp. aureus N315
1 HssR

Staphylococcus capitis SK14
1 HssR

Staphylococcus epidermidis ATCC 12228
1 HssR

Staphylococcus carnosus subsp. carnosus TM300
1 HssR

Staphylococcus haemolyticus JCSC1435
1 HssR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 HssR

Macrococcus caseolyticus JCSC5402
Heme efflux
TF NreC
3 NreC

Staphylococcus aureus subsp. aureus N315
3 NreC

Staphylococcus capitis SK14
3 NreC

Staphylococcus epidermidis ATCC 12228
3 NreC

Staphylococcus carnosus subsp. carnosus TM300
3 NreC

Staphylococcus haemolyticus JCSC1435
2 NreC

Macrococcus caseolyticus JCSC5402
Nitrate and nitrite respiration
TF SaeR
22 SaeR

Staphylococcus aureus subsp. aureus N315
3 SaeR

Staphylococcus capitis SK14
3 SaeR

Staphylococcus epidermidis ATCC 12228
2 SaeR

Staphylococcus carnosus subsp. carnosus TM300
Virulence
PurR TF PurR
4 PurR

Staphylococcus aureus subsp. aureus N315
3 PurR

Staphylococcus capitis SK14
3 PurR

Staphylococcus epidermidis ATCC 12228
3 PurR

Staphylococcus carnosus subsp. carnosus TM300
4 PurR

Staphylococcus haemolyticus JCSC1435
4 PurR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
4 PurR

Macrococcus caseolyticus JCSC5402
Purine metabolism
Rex TF Rex
17 Rex

Staphylococcus aureus subsp. aureus N315
10 Rex

Staphylococcus capitis SK14
12 Rex

Staphylococcus epidermidis ATCC 12228
7 Rex

Staphylococcus carnosus subsp. carnosus TM300
11 Rex

Staphylococcus haemolyticus JCSC1435
6 Rex

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
5 Rex

Macrococcus caseolyticus JCSC5402
Energy metabolism
RpiR TF GlvR
1 GlvR

Staphylococcus aureus subsp. aureus N315
1 GlvR

Staphylococcus capitis SK14
1 GlvR

Staphylococcus epidermidis ATCC 12228
1 GlvR

Staphylococcus haemolyticus JCSC1435
1 GlvR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Maltose utilization
TF MurR
1 MurR

Staphylococcus aureus subsp. aureus N315
1 MurR

Staphylococcus capitis SK14
1 MurR

Staphylococcus epidermidis ATCC 12228
1 MurR

Staphylococcus carnosus subsp. carnosus TM300
1 MurR

Staphylococcus haemolyticus JCSC1435
1 MurR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
N-acetylmuramate utilization
TF NanR
4 NanR

Staphylococcus aureus subsp. aureus N315
4 NanR

Staphylococcus carnosus subsp. carnosus TM300
5 NanR

Staphylococcus haemolyticus JCSC1435
5 NanR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Sialic acid utilization; N-acetylglucosamine utilization
Rrf2 TF CymR
12 CymR

Staphylococcus aureus subsp. aureus N315
9 CymR

Staphylococcus capitis SK14
10 CymR

Staphylococcus epidermidis ATCC 12228
9 CymR

Staphylococcus carnosus subsp. carnosus TM300
8 CymR

Staphylococcus haemolyticus JCSC1435
10 CymR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
6 CymR

Macrococcus caseolyticus JCSC5402
Cysteine metabolism
SorC TF CggR
1 CggR

Staphylococcus aureus subsp. aureus N315
1 CggR

Staphylococcus capitis SK14
1 CggR

Staphylococcus epidermidis ATCC 12228
1 CggR

Staphylococcus carnosus subsp. carnosus TM300
1 CggR

Staphylococcus haemolyticus JCSC1435
1 CggR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 CggR

Macrococcus caseolyticus JCSC5402
Glycolysis
TetR TF IcaR
2 IcaR

Staphylococcus aureus subsp. aureus N315
2 IcaR

Staphylococcus capitis SK14
Intercellular adhesion
TrpR TF HisR
4 HisR

Staphylococcus aureus subsp. aureus N315
3 HisR

Staphylococcus capitis SK14
4 HisR

Staphylococcus epidermidis ATCC 12228
4 HisR

Staphylococcus carnosus subsp. carnosus TM300
3 HisR

Staphylococcus haemolyticus JCSC1435
4 HisR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 HisR

Macrococcus caseolyticus JCSC5402
Histidine biosynthesis
RF00050 RNA FMN
2 FMN

Staphylococcus aureus subsp. aureus N315
2 FMN

Staphylococcus capitis SK14
2 FMN

Staphylococcus epidermidis ATCC 12228
2 FMN

Staphylococcus carnosus subsp. carnosus TM300
2 FMN

Staphylococcus haemolyticus JCSC1435
2 FMN

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 FMN

Macrococcus caseolyticus JCSC5402
Riboflavin biosynthesis
RF00059 RNA TPP
2 TPP

Staphylococcus aureus subsp. aureus N315
4 TPP

Staphylococcus capitis SK14
5 TPP

Staphylococcus epidermidis ATCC 12228
5 TPP

Staphylococcus carnosus subsp. carnosus TM300
4 TPP

Staphylococcus haemolyticus JCSC1435
4 TPP

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
6 TPP

Macrococcus caseolyticus JCSC5402
Thiamine biosynthesis
RF00080 RNA yybP-ykoY
1 yybP-ykoY

Staphylococcus aureus subsp. aureus N315
1 yybP-ykoY

Staphylococcus capitis SK14
1 yybP-ykoY

Staphylococcus epidermidis ATCC 12228
1 yybP-ykoY

Staphylococcus carnosus subsp. carnosus TM300
1 yybP-ykoY

Staphylococcus haemolyticus JCSC1435
1 yybP-ykoY

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 yybP-ykoY

Macrococcus caseolyticus JCSC5402
RF00162 RNA SAM
4 SAM

Staphylococcus aureus subsp. aureus N315
4 SAM

Staphylococcus capitis SK14
4 SAM

Staphylococcus epidermidis ATCC 12228
8 SAM

Staphylococcus carnosus subsp. carnosus TM300
6 SAM

Staphylococcus haemolyticus JCSC1435
6 SAM

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
8 SAM

Macrococcus caseolyticus JCSC5402
Methionine biosynthesis
RF00167 RNA Purine
1 Purine

Staphylococcus aureus subsp. aureus N315
1 Purine

Staphylococcus capitis SK14
1 Purine

Staphylococcus epidermidis ATCC 12228
1 Purine

Staphylococcus carnosus subsp. carnosus TM300
1 Purine

Staphylococcus haemolyticus JCSC1435
1 Purine

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 Purine

Macrococcus caseolyticus JCSC5402
Purine metabolism
RF00168 RNA Lysine
2 Lysine

Staphylococcus aureus subsp. aureus N315
2 Lysine

Staphylococcus capitis SK14
2 Lysine

Staphylococcus epidermidis ATCC 12228
2 Lysine

Staphylococcus carnosus subsp. carnosus TM300
2 Lysine

Staphylococcus haemolyticus JCSC1435
2 Lysine

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 Lysine

Macrococcus caseolyticus JCSC5402
Lysine biosynthesis
RF00230 RNA T-box(Ala)
1 T-box(Ala)

Staphylococcus aureus subsp. aureus N315
1 T-box(Ala)

Staphylococcus capitis SK14
1 T-box(Ala)

Staphylococcus epidermidis ATCC 12228
1 T-box(Ala)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Ala)

Staphylococcus haemolyticus JCSC1435
1 T-box(Ala)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Ala)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Asn)
1 T-box(Asn)

Staphylococcus aureus subsp. aureus N315
1 T-box(Asn)

Staphylococcus capitis SK14
1 T-box(Asn)

Staphylococcus epidermidis ATCC 12228
1 T-box(Asn)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Asn)

Staphylococcus haemolyticus JCSC1435
1 T-box(Asn)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Asn)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Cys)
1 T-box(Cys)

Staphylococcus aureus subsp. aureus N315
1 T-box(Cys)

Staphylococcus capitis SK14
1 T-box(Cys)

Staphylococcus epidermidis ATCC 12228
1 T-box(Cys)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Cys)

Staphylococcus haemolyticus JCSC1435
1 T-box(Cys)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Cys)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Gly)
1 T-box(Gly)

Staphylococcus aureus subsp. aureus N315
1 T-box(Gly)

Staphylococcus capitis SK14
1 T-box(Gly)

Staphylococcus epidermidis ATCC 12228
1 T-box(Gly)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Gly)

Staphylococcus haemolyticus JCSC1435
1 T-box(Gly)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Gly)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Ile)
1 T-box(Ile)

Staphylococcus aureus subsp. aureus N315
1 T-box(Ile)

Staphylococcus capitis SK14
1 T-box(Ile)

Staphylococcus epidermidis ATCC 12228
1 T-box(Ile)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Ile)

Staphylococcus haemolyticus JCSC1435
1 T-box(Ile)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Ile)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Leu)
1 T-box(Leu)

Staphylococcus aureus subsp. aureus N315
1 T-box(Leu)

Staphylococcus capitis SK14
1 T-box(Leu)

Staphylococcus epidermidis ATCC 12228
1 T-box(Leu)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Leu)

Staphylococcus haemolyticus JCSC1435
1 T-box(Leu)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Leu)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Met)
1 T-box(Met)

Staphylococcus aureus subsp. aureus N315
1 T-box(Met)

Staphylococcus capitis SK14
1 T-box(Met)

Staphylococcus epidermidis ATCC 12228
2 T-box(Met)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Met)

Staphylococcus haemolyticus JCSC1435
1 T-box(Met)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Met)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Phe)
1 T-box(Phe)

Staphylococcus aureus subsp. aureus N315
1 T-box(Phe)

Staphylococcus capitis SK14
1 T-box(Phe)

Staphylococcus epidermidis ATCC 12228
1 T-box(Phe)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Phe)

Staphylococcus haemolyticus JCSC1435
1 T-box(Phe)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Phe)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Ser)
1 T-box(Ser)

Staphylococcus aureus subsp. aureus N315
1 T-box(Ser)

Staphylococcus capitis SK14
1 T-box(Ser)

Staphylococcus epidermidis ATCC 12228
1 T-box(Ser)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Ser)

Staphylococcus haemolyticus JCSC1435
1 T-box(Ser)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Ser)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Thr)
1 T-box(Thr)

Staphylococcus aureus subsp. aureus N315
1 T-box(Thr)

Staphylococcus capitis SK14
1 T-box(Thr)

Staphylococcus epidermidis ATCC 12228
2 T-box(Thr)

Staphylococcus carnosus subsp. carnosus TM300
2 T-box(Thr)

Staphylococcus haemolyticus JCSC1435
1 T-box(Thr)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Thr)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Trp)
1 T-box(Trp)

Staphylococcus aureus subsp. aureus N315
1 T-box(Trp)

Staphylococcus capitis SK14
1 T-box(Trp)

Staphylococcus epidermidis ATCC 12228
1 T-box(Trp)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Trp)

Staphylococcus haemolyticus JCSC1435
1 T-box(Trp)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Amino acid metabolism
RNA T-box(Tyr)
1 T-box(Tyr)

Staphylococcus aureus subsp. aureus N315
2 T-box(Tyr)

Staphylococcus capitis SK14
1 T-box(Tyr)

Staphylococcus epidermidis ATCC 12228
1 T-box(Tyr)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Tyr)

Staphylococcus haemolyticus JCSC1435
1 T-box(Tyr)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Tyr)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RNA T-box(Val)
1 T-box(Val)

Staphylococcus aureus subsp. aureus N315
1 T-box(Val)

Staphylococcus epidermidis ATCC 12228
1 T-box(Val)

Staphylococcus carnosus subsp. carnosus TM300
1 T-box(Val)

Staphylococcus haemolyticus JCSC1435
1 T-box(Val)

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 T-box(Val)

Macrococcus caseolyticus JCSC5402
Amino acid metabolism
RF00234 RNA glmS
1 glmS

Staphylococcus aureus subsp. aureus N315
1 glmS

Staphylococcus capitis SK14
1 glmS

Staphylococcus epidermidis ATCC 12228
1 glmS

Staphylococcus carnosus subsp. carnosus TM300
1 glmS

Staphylococcus haemolyticus JCSC1435
1 glmS

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 glmS

Macrococcus caseolyticus JCSC5402
Amino sugar metabolism
RF00442 RNA ykkC-yxkD
1 ykkC-yxkD

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
Multidrug resistance
RF00504 RNA Glycine
1 Glycine

Staphylococcus aureus subsp. aureus N315
1 Glycine

Staphylococcus capitis SK14
1 Glycine

Staphylococcus epidermidis ATCC 12228
1 Glycine

Staphylococcus carnosus subsp. carnosus TM300
1 Glycine

Staphylococcus haemolyticus JCSC1435
1 Glycine

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 Glycine

Macrococcus caseolyticus JCSC5402
Glycine metabolism
RF00515 RNA PyrR
1 PyrR

Staphylococcus aureus subsp. aureus N315
1 PyrR

Staphylococcus capitis SK14
2 PyrR

Staphylococcus epidermidis ATCC 12228
2 PyrR

Staphylococcus carnosus subsp. carnosus TM300
2 PyrR

Staphylococcus haemolyticus JCSC1435
2 PyrR

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
2 PyrR

Macrococcus caseolyticus JCSC5402
Pyrimidine metabolism
RF00522 RNA PreQ1
2 PreQ1

Staphylococcus aureus subsp. aureus N315
2 PreQ1

Staphylococcus capitis SK14
2 PreQ1

Staphylococcus epidermidis ATCC 12228
2 PreQ1

Staphylococcus carnosus subsp. carnosus TM300
2 PreQ1

Staphylococcus haemolyticus JCSC1435
2 PreQ1

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 PreQ1

Macrococcus caseolyticus JCSC5402
Queuosine biosynthesis
RF00555 RNA L13_leader
1 L13_leader

Staphylococcus aureus subsp. aureus N315
1 L13_leader

Staphylococcus capitis SK14
1 L13_leader

Staphylococcus epidermidis ATCC 12228
1 L13_leader

Staphylococcus carnosus subsp. carnosus TM300
1 L13_leader

Staphylococcus haemolyticus JCSC1435
1 L13_leader

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 L13_leader

Macrococcus caseolyticus JCSC5402
Ribosome biogenesis
RF00556 RNA L19_leader
1 L19_leader

Staphylococcus aureus subsp. aureus N315
1 L19_leader

Staphylococcus capitis SK14
1 L19_leader

Staphylococcus epidermidis ATCC 12228
1 L19_leader

Staphylococcus carnosus subsp. carnosus TM300
1 L19_leader

Staphylococcus haemolyticus JCSC1435
1 L19_leader

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 L19_leader

Macrococcus caseolyticus JCSC5402
Ribosome biogenesis
RF00557 RNA L10_leader
1 L10_leader

Staphylococcus aureus subsp. aureus N315
1 L10_leader

Staphylococcus capitis SK14
1 L10_leader

Staphylococcus epidermidis ATCC 12228
1 L10_leader

Staphylococcus carnosus subsp. carnosus TM300
1 L10_leader

Staphylococcus haemolyticus JCSC1435
1 L10_leader

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 L10_leader

Macrococcus caseolyticus JCSC5402
Ribosome biogenesis
RF00558 RNA L20_leader
1 L20_leader

Staphylococcus aureus subsp. aureus N315
1 L20_leader

Staphylococcus capitis SK14
1 L20_leader

Staphylococcus epidermidis ATCC 12228
1 L20_leader

Staphylococcus carnosus subsp. carnosus TM300
1 L20_leader

Staphylococcus haemolyticus JCSC1435
1 L20_leader

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 L20_leader

Macrococcus caseolyticus JCSC5402
Ribosome biogenesis
RF00559 RNA L21_leader
1 L21_leader

Staphylococcus capitis SK14
1 L21_leader

Staphylococcus epidermidis ATCC 12228
1 L21_leader

Staphylococcus carnosus subsp. carnosus TM300
1 L21_leader

Staphylococcus haemolyticus JCSC1435
1 L21_leader

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305
1 L21_leader

Macrococcus caseolyticus JCSC5402
Ribosome biogenesis