Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs in Chlamydiales taxonomic group

General statistics
Genomes 7
TF regulogs 4
TF regulons 21
TF binding sites 39
RNA regulogs 0
RNA regulons 0
RNA sites 0

This collection involves all regulons that were tentatively predicted by applying integrative comparative genomic approach to a single taxonomic group of closely-related genomes. To infer the regulons operated by transcription factors (TFs), we combined the identification of TF binding sites and cross-genome comparison of regulons with the analysis of the genomic and functional context of candidate target genes. To infer the regulons operated by regulatory RNAs such as riboswitches, we identified candidate RNA regulatory elements using HMM profiles and further analyzed their genomic and functional context.

Studied genomes and reconstructed regulon statistics
TF RNA Total
Genomes Regulons Sites Regulons Sites Regulons Sites
Chlamydia muridarum Nigg 2 4 0 0 2 4
Chlamydia trachomatis D/UW-3/CX 3 5 0 0 3 5
Chlamydophila abortus S26/3 3 6 0 0 3 6
Chlamydophila caviae GPIC 4 7 0 0 4 7
Chlamydophila felis Fe/C-56 4 7 0 0 4 7
Chlamydophila pneumoniae AR39 3 6 0 0 3 6
Parachlamydia sp. UWE25 2 4 0 0 2 4
Genomic distribution of regulons
Family Type Regulator Function
ArgR TF ArgR
1 ArgR

Chlamydophila abortus S26/3
1 ArgR

Chlamydophila pneumoniae AR39
1 ArgR

Chlamydophila caviae GPIC
1 ArgR

Chlamydophila felis Fe/C-56
Arginine biosynthesis
HrcA TF HrcA
2 HrcA

Chlamydia muridarum Nigg
2 HrcA

Chlamydophila abortus S26/3
2 HrcA

Chlamydophila pneumoniae AR39
2 HrcA

Chlamydophila caviae GPIC
2 HrcA

Chlamydia trachomatis D/UW-3/CX
2 HrcA

Parachlamydia sp. UWE25
2 HrcA

Chlamydophila felis Fe/C-56
Heat shock response
NrdR TF NrdR
1 NrdR

Chlamydia muridarum Nigg
1 NrdR

Chlamydophila abortus S26/3
1 NrdR

Chlamydophila pneumoniae AR39
1 NrdR

Chlamydophila caviae GPIC
1 NrdR

Chlamydia trachomatis D/UW-3/CX
1 NrdR

Parachlamydia sp. UWE25
1 NrdR

Chlamydophila felis Fe/C-56
Deoxyribonucleotide biosynthesis
TrpR TF TrpR
1 TrpR

Chlamydophila caviae GPIC
1 TrpR

Chlamydia trachomatis D/UW-3/CX
1 TrpR

Chlamydophila felis Fe/C-56
Tryptophan biosynthesis