Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs in Enterococcaceae taxonomic group

General statistics
Genomes 2
TF regulogs 15
TF regulons 24
TF binding sites 73
RNA regulogs 0
RNA regulons 0
RNA sites 0

This collection involves all regulons that were tentatively predicted by applying integrative comparative genomic approach to a single taxonomic group of closely-related genomes. To infer the regulons operated by transcription factors (TFs), we combined the identification of TF binding sites and cross-genome comparison of regulons with the analysis of the genomic and functional context of candidate target genes. To infer the regulons operated by regulatory RNAs such as riboswitches, we identified candidate RNA regulatory elements using HMM profiles and further analyzed their genomic and functional context.

Studied genomes and reconstructed regulon statistics
TF RNA Total
Genomes Regulons Sites Regulons Sites Regulons Sites
Enterococcus faecalis V583 15 49 0 0 15 49
Enterococcus faecium DO 9 24 0 0 9 24
Genomic distribution of regulons
Family Type Regulator Function
AraC TF RhaR
1 RhaR

Enterococcus faecalis V583
1 RhaR

Enterococcus faecium DO
Rhamnose utilization
DtxR TF MntR
4 MntR

Enterococcus faecalis V583
1 MntR

Enterococcus faecium DO
Manganese homeostasis
FUR TF Fur
6 Fur

Enterococcus faecalis V583
4 Fur

Enterococcus faecium DO
Iron homeostasis
TF Zur
5 Zur

Enterococcus faecalis V583
5 Zur

Enterococcus faecium DO
Zinc homeostasis
GntR/MocR TF EF0117
2 EF0117

Enterococcus faecalis V583
2 EF0117

Enterococcus faecium DO
TF PdxR
4 PdxR

Enterococcus faecalis V583
1 PdxR

Enterococcus faecium DO
Pyridoxine biosynthesis
GntR/Others TF AgaR2
1 AgaR2

Enterococcus faecalis V583
1 AgaR2

Enterococcus faecium DO
N-acetylgalactosamine utilization
TF EF1676
1 EF1676

Enterococcus faecalis V583
Multidrug resistance; Multidrug efflux
TF NagR
7 NagR

Enterococcus faecalis V583
3 NagR

Enterococcus faecium DO
N-acetylglucosamine utilization
TF TreR
3 TreR

Enterococcus faecalis V583
Trehalose utilization
LacI TF BglR
1 BglR

Enterococcus faecalis V583
Beta-glucosides utilization
TF EF1410
2 EF1410

Enterococcus faecalis V583
Sugar utilization
TF UriR
1 UriR

Enterococcus faecalis V583
1 UriR

Enterococcus faecium DO
Nucleoside utilization
ROK TF XylR
2 XylR

Enterococcus faecalis V583
Xylose utilization
SdaR TF SdaR
2 SdaR

Enterococcus faecalis V583
Glycerate utilization