Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Collection of regulogs for GEMM_RNA_motif (RF01051) RNA regulatory element

The Cyclic di-GMP riboswitch, also known as GEMM RNA motif, is a highly conserved RNA structure that is involved in regulation of a large variety of microbial processes including virulence, motility, and biofilm formation. It serves as a riboswitch that binds directly to cyclic di-guanosine monophosphate [18635805]. Cyclic di-GMP is a second messenger used in signal transduction in a wide variety of bacteria. Cyclic di-GMP is synthesized by proteins with diguanylate cyclase activity. Cyclic di-GMP riboswitch was originally identified by bioinformatics as a conserved RNA-like structure called the "GEMM motif" [17621584]. more

Phylum Regulog RNA regulons (studied genomes) RNA sites
Cyanobacteria GEMM_RNA_motif - Cyanobacteria 2 (14) 6
Deinococcus-Thermus GEMM_RNA_motif - Deinococcus-Thermus 1 (5) 3
Firmicutes GEMM_RNA_motif - Bacillales 7 (11) 9
Firmicutes GEMM_RNA_motif - Clostridiaceae 12 (20) 29
Proteobacteria GEMM_RNA_motif - Enterobacteriales 1 (12) 1
Proteobacteria GEMM_RNA_motif - Ralstonia 1 (6) 1
Proteobacteria GEMM_RNA_motif - Shewanellaceae 13 (16) 20
Proteobacteria GEMM_RNA_motif - Vibrionales 10 (10) 15
Proteobacteria/delta GEMM_RNA_motif - Desulfovibrionales 3 (10) 5