Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for TPP (RF00059) RNA regulatory element

The TPP riboswitch, also known as THI element and Thi-box riboswitch, is a highly conserved RNA structure that is involved in regulation of thiamin metabolism in Archaea, Bacteria and Eukaryotes (plants). It serves as a riboswitch [12410317, 12464185] that binds directly to thiamine pyrophosphate (TPP) to regulate gene expression through a variety of mechanisms [12756322, 12376536]. In Bacteria, THI elements are located in 5?-untranslated regions of various genes involved in thiamin metabolism and involved in transcriptional or translational regulation. TPP is the active form of thiamine (vitamin B1), an essential coenzyme synthesized in bacteria by coupling of hydroxymethylpyrimidine (HMP) and hydroxyethylthiazole (HET) moieties. more

Phylum Regulog RNA regulons (studied genomes) RNA sites
Actinobacteria TPP - Bifidobacteriaceae 9 (9) 34
Actinobacteria TPP - Corynebacteriaceae 8 (8) 23
Actinobacteria TPP - Mycobacteriaceae 9 (9) 22
Actinobacteria TPP - Streptomycetaceae 4 (4) 13
Bacteroidetes TPP - Bacteroidaceae 11 (11) 19
Chlorobiales TPP - Chlorobiales 9 (11) 11
Chloroflexi TPP - Chloroflexia 5 (5) 14
Cyanobacteria TPP - Cyanobacteria 14 (14) 14
Deinococcus-Thermus TPP - Deinococcus-Thermus 5 (5) 10
Firmicutes TPP - Bacillales 11 (11) 47
Firmicutes TPP - Clostridia-3 14 (14) 34
Firmicutes TPP - Clostridiaceae 20 (20) 62
Firmicutes TPP - Lactobacillaceae 14 (15) 36
Firmicutes TPP - Staphylococcaceae 7 (7) 30
Firmicutes TPP - Streptococcaceae 15 (15) 23
Firmicutes TPP - Thermoanaerobacterales 7 (7) 17
Proteobacteria TPP - Burkholderia 8 (8) 18
Proteobacteria TPP - Caulobacterales 4 (4) 4
Proteobacteria TPP - Enterobacteriales 12 (12) 38
Proteobacteria TPP - Pasteurellales 9 (9) 20
Proteobacteria TPP - Pseudomonadaceae 8 (8) 9
Proteobacteria TPP - Ralstonia 6 (6) 6
Proteobacteria TPP - Rhizobiales 14 (15) 30
Proteobacteria TPP - Rhodobacterales 15 (15) 30
Proteobacteria TPP - Shewanellaceae 16 (16) 31
Proteobacteria TPP - Vibrionales 10 (10) 30
Proteobacteria/Alpha TPP - Rhodospirillales 9 (9) 15
Proteobacteria/Alpha TPP - Sphingomonadales 7 (7) 7
Proteobacteria/Beta TPP - Comamonadaceae 11 (11) 25
Proteobacteria/Beta TPP - Various betaproteobacteria 12 (12) 16
Proteobacteria/Delta TPP - Desulfovibrionales 8 (10) 17
Proteobacteria/Delta TPP - Desulfuromonadales 8 (9) 15
Proteobacteria/Epsilon TPP - Campylobacteraceae 4 (9) 5
Proteobacteria/Epsilon TPP - Helicobacteraceae 3 (8) 3
Proteobacteria/Gamma TPP - Alteromonadales 9 (9) 13
Proteobacteria/Gamma TPP - Francisellaceae 3 (3) 4
Proteobacteria/Gamma TPP - Moraxellaceae 4 (4) 5
Proteobacteria/Gamma TPP - Oceanospirillales/Alteromonadales 11 (12) 23
Proteobacteria/Gamma TPP - Psychromonadaceae/Aeromonadales 6 (6) 14
Proteobacteria/Gamma TPP - Xanthomonadales 4 (4) 5
Thermotogae TPP - Thermotogales 11 (11) 16