Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Collection of regulogs for PreQ1 (RF00522) RNA regulatory element

The PreQ1 riboswitch is a highly conserved RNA structure that is involved in regulation of the nucleoside queuosine biosynthesis in bacteria. It serves as a riboswitch that binds directly to preQ1 (pre-queuosine1 or 7-aminomethyl-7-deazaguanine), an intermediate of the queuosine pathway [17384645]. Queuosine is a modified nucleoside that is present in certain tRNAs in bacteria and eukaryotes. In bacteria, queuosine is either synthesized from GTP via a committed metabolic pathway [14660578] or it is salvaged from the environment via queuosine precursor-specific transport systems [20497229]. The preQ1 riboswitch was originally identified by bioinformatics as a conserved RNA-like structure located upstream of ykvJKLM (queCDEF) operon in Bacillus subtilis and related genomes [15096624]. more

Phylum Regulog RNA regulons (studied genomes) RNA sites
Firmicutes PreQ1 - Bacillales 11 (11) 15
Firmicutes PreQ1 - Clostridiaceae 17 (20) 23
Firmicutes PreQ1 - Lactobacillaceae 5 (15) 9
Firmicutes PreQ1 - Staphylococcaceae 7 (7) 13
Firmicutes PreQ1 - Streptococcaceae 2 (15) 2
Proteobacteria PreQ1 - Pasteurellales 8 (9) 9
Proteobacteria PreQ1 - Rhodobacterales 1 (15) 1