Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Collection of regulogs for PyrR (RF00515) RNA regulatory element

The PyrR binding site motif is an RNA element that was found upstream of a variety of genes involved in pyrimidine biosynthesis and transport in Bacillus subtilis and related Gram-positive bacteria from the Firmicutes phylum. The PyrR RNA element is a binding site of the PyrR regulatory protein that binds the leader RNA regions of the PyrR regulon target genes in the presence of uridine nucleotides [11726695]. UMP or UDP nucleotides are less effective co-regulators of PyrR in comparison with UTP. The PyrR protein binds an RNA-binding loop of the PyrR RNA element, allowing a terminator hairpin to form and repressing the downstream genes [12896995]. more

Phylum Regulog RNA regulons (studied genomes) RNA sites
Actinobacteria PyrR - Corynebacteriaceae 6 (8) 6
Actinobacteria PyrR - Mycobacteriaceae 8 (9) 8
Chloroflexi PyrR - Chloroflexia 3 (5) 3
Deinococcus-Thermus PyrR - Deinococcus-Thermus 2 (5) 2
Firmicutes PyrR - Bacillales 11 (11) 31
Firmicutes PyrR - Clostridiaceae 13 (20) 45
Firmicutes PyrR - Lactobacillaceae 14 (15) 49
Firmicutes PyrR - Staphylococcaceae 7 (7) 13
Firmicutes PyrR - Streptococcaceae 15 (15) 60