Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Collection of regulogs for glmS (RF00234) RNA regulatory element

The Glucosamine-6-phosphate activated ribozyme (glmS ribozyme) is an RNA structural motif that functions both as ribozyme and metabolite-responsive riboswitch. The glmS RNA motif was originally identified upstream of the glmS gene in numerous Gram-positive bacteria from the Firmicutes phylum [15096624]. The GlmS enzyme catalyzes the synthesis of glucosamine-6-phosphate (GlcN6P), and the GlmS ribozyme is dependent on GlcN6P to achieve catalysis of its own mRNA cleavage [15029187]. This cleavage leads to the degradation of the mRNA that contains the ribozyme, and ultimately lowers expression of the glmS gene [18079181]. more

Phylum Regulog RNA regulons (studied genomes) RNA sites
Chloroflexi glmS - Chloroflexia 5 (5) 5
Deinococcus-Thermus glmS - Deinococcus-Thermus 3 (5) 3
Firmicutes glmS - Bacillales 11 (11) 11
Firmicutes glmS - Clostridiaceae 17 (20) 17
Firmicutes glmS - Lactobacillaceae 1 (15) 1
Firmicutes glmS - Staphylococcaceae 7 (7) 7