Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Collection of regulogs for Cobalamin (RF00174) RNA regulatory element

The Cobalamin riboswitch, also known as B12 element and AdoCbl riboswitch, is a highly con-served RNA structure that is involved in regulation of coenzyme B12 metabolism in Bacteria. It serves as a riboswitch [12323379] that binds directly to coenzyme B12, or adenosylcobalamin (AdoCbl) to regulate bacterial gene expression through either transcriptional or translational attenuation mechanisms [14704351]. Cobalamin belongs to a class of the most structurally complex cofactors synthesized by bacteria. The distinctive feature of these cofactors is their tetrapyrrole-derived framework with a centrally chelated metal ion (e.g., cobalt in B12). more

Phylum Regulog RNA regulons (studied genomes) RNA sites
Actinobacteria Cobalamin - Corynebacteriaceae 4 (8) 6
Actinobacteria Cobalamin - Mycobacteriaceae 9 (9) 21
Bacteroidetes Cobalamin - Bacteroidaceae 11 (11) 65
Chlorobiales Cobalamin - Chlorobiales 11 (11) 34
Chloroflexi Cobalamin - Chloroflexia 5 (5) 13
Cyanobacteria Cobalamin - Cyanobacteria 11 (14) 20
Deinococcus-Thermus Cobalamin - Deinococcus-Thermus 5 (5) 12
Firmicutes Cobalamin - Bacillales 9 (11) 18
Firmicutes Cobalamin - Clostridiaceae 19 (20) 50
Firmicutes Cobalamin - Lactobacillaceae 1 (15) 1
Proteobacteria Cobalamin - Burkholderia 8 (8) 38
Proteobacteria Cobalamin - Caulobacterales 4 (4) 7
Proteobacteria Cobalamin - Enterobacteriales 11 (12) 16
Proteobacteria Cobalamin - Pseudomonadaceae 8 (8) 33
Proteobacteria Cobalamin - Ralstonia 6 (6) 7
Proteobacteria Cobalamin - Rhizobiales 14 (15) 57
Proteobacteria Cobalamin - Rhodobacterales 15 (15) 48
Proteobacteria Cobalamin - Shewanellaceae 16 (16) 34
Proteobacteria Cobalamin - Vibrionales 10 (10) 13
Proteobacteria/delta Cobalamin - Desulfovibrionales 9 (10) 23
Thermotogae Cobalamin - Thermotogales 11 (11) 20