Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 4.0 --

Collection of regulogs for S15 (RF00114) RNA regulatory element

The ribosomal S15 leader is an RNA regulatory element that was found upstream of the Escherichia coli gene rpsO encoding the small ribosomal protein S15.The expression of rpsO is autoregulated through the formation of a pseudoknot in the leader mRNA [8955900]. This secondary RNA structure has an alternative structure, a combination of three hairpins, that are responsible for translational regulation of the S15 protein expression. The 30S ribosomal subunit binds efficiently to the pseudoknot because the Shine-Dalgarno sequence is presumed to be fully exposed. When the concentration of free S15 is low, the pseudoknot opens, the initiation complex is formed and translation can proceed. more

Phylum Regulog RNA regulons (studied genomes) RNA sites
Actinobacteria S15 - Corynebacteriaceae 7 (8) 7
Firmicutes S15 - Clostridiaceae 3 (20) 3
Firmicutes S15 - Lactobacillaceae 9 (15) 9
Firmicutes S15 - Streptococcaceae 15 (15) 15
Proteobacteria S15 - Enterobacteriales 12 (12) 12
Proteobacteria S15 - Pasteurellales 9 (9) 10
Proteobacteria S15 - Pseudomonadaceae 8 (8) 8
Proteobacteria S15 - Rhodobacterales 9 (15) 9
Proteobacteria S15 - Shewanellaceae 16 (16) 16
Proteobacteria S15 - Vibrionales 9 (10) 9