The RegPrecise is a database for capturing, visualization and analysis of transcription factor regulons that were reconstructed by the comparative genomic approach in a wide variety of prokaryotic genomes.more
Browse collections that organize the reconstructed regulons by phylogenetic, structural or functional properties of regulators.
For each regulog, the propagation procedure checks for the presence of orthologs for both a transcription factor gene and target genes (regulog members), and then performs search for candidate TF-binding sites in upstream regions of orthologous target genes
This procedure is considered to be accurate and conservative since it relies on the manually curated regulons and does not make an attempt for automatic prediction of new members of regulon.
Recent update, March 2016
More that 250 new TF regulogs for various TFs. Current release include 32 novel taxonomy collections of regulogs from Proteobacteria (17 new taxa), Firmicutes (6 taxa), Actinobacteria (5 taxa) and other phyla. We added 15 novel collections of regulogs for orthologous TFs including DasR, HisR, MntR, PdxR, PhrR, in Bacteria and CblR, Phr, RbkR, ThiR, in Archaea.
Upcoming, October 2016
A comprehensive collection of motifs reconstructed by comparative anlaysis for all major transcription factor families across thousands of bacterial genomes.